Selected
Readings in Vision and Graphics
edited by Luc Van Gool, Gábor
Székely, Markus Gross, Bernt Schiele
Volume 48
Martin von
Siebenthal
Analysis and
Modelling of Respiratory
Liver Motion using 4DMRI
First edition 2008, 166 pages, € 64,00. ISBN 3-86628-194-3
This thesis describes methods for imaging, analysis, and modelling of
respiratory organ motion in order to improve planning and targeting in
radiation therapy. To study respiratory motion in detail, a method for time
resolved volumetric magnetic resonance imaging (4DMRI) was developed.
The analysis of 4DMRI data from volunteers provided new insights into
the intrafraction motion of the liver during free breathing. Simulations of
different gating scenarios demonstrated the large targeting errors that can
result from intrafraction drifts in gated treatment with external respiratory
signals.
In order to improve targeting, we show how to capture the observed
motion in a statistical model and how to use this model as prior knowledge
together with possibly few patient-specific measurements. The obtained motion
data was further used to evaluate the dosimetric impact of respiratory motion
in radiation therapy with scanned proton beams.
About the author:
Martin von Siebenthal received his
M.Sc. in Electrical Engineering and Information Technology and the ETH Zurich
Medal for an outstanding master thesis in 2004. During his doctoral studies he
worked at the Computer Vision Laboratory of ETH
Keywords / Schlagwörter:
Magnetic Resonance Imaging, Organ Motion, Respiration, Breathing, Radiation
Therapy, Proton Therapy, 4DMRI, Registration, Statistical Modelling, Respiratory
Gating
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