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Selected Readings in
Vision and Graphics
edited by Luc Van Gool, Gábor Székely,
Markus Gross, Bernt Schiele
Volume 54
Stefan Saur
Quantitative Assessment of
Atherosclerosis in
Coronary Arteries
2009. XVI, 150 pages. EUR 64,00.
ISBN 978-3-86628-281-0
Cardiovascular
diseases represent the leading cause of death in developed countries. In the
presence of atherosclerosis, plaques develop by the accumulation of lipid or
calcified deposits in the vessel walls. These days, computed tomography (CT)
has emerged as a robust and accurate modality for the assessment of
atherosclerosis. However, as automatic software tools are still missing, the
assessment is done manually which induces errors in form of observer
variabilities for the detection and measurement of plaques.
This
book aims in reducing these aforementioned variabilities by presenting
automatic
and semi-automatic algorithms for an
improved assessment of atherosclerosis in coronary arteries.
Firstly,
a robust method for the volumetric assessment of calcified plaques in
non-enhanced CT data sets is presented. Then, a framework for the automatic
extraction of calcified plaques is discussed which includes algorithms for the
extraction of anatomical features. Afterwards, Dual Energy CT is considered to
propose an algorithm for contrast enhancement between tissues as compared to a
conventional CT examination. Finally, spatial plaque distribution patterns are
evaluated. Knowledge about these patterns is used to propose a guided review of
coronary segments for improving manual plaque detection.
About hte Author
Stefan Saur obtained his M.Sc. (Dipl.-Ing.)
degree in Electrical Engineering and Information Technology from the University
of Karlsruhe, Germany, in 2005. He performed his master
thesis at Siemens Corporate Research in Princeton, New Jersey, USA in the field
of medical imaging. From 2005 to 2009, he was research assistant and Ph.D.
student at the Computer Vision Laboratory of ETH Zurich, Switzerland, with Prof. Gábor Székely.
In 2009, he finished his doctoral thesis entitled “Quantitative Assessment of
Atherosclerosis in Coronary Arteries” and was awarded a Ph.D. degree (Dr. sc. ETH Zürich) from ETH
Zurich.
Keywords / Schlagwörter:
Cardiovascular diseases, atherosclerosis, computed
tomography (CT), coronary arteries, calcified plaques
Reihe " Selected Readings in Vision and Graphics
"
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