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Selected Readings in
Vision and Graphics
edited by Luc Van Gool, Gábor Székely,
Markus Gross, Bernt Schiele
Volume 63
Robert H. P.
McGregor
Enhancing Medical Images with High
Quality Blood Flow Information
2010. XVI, 172 pages. EUR 64,00.
ISBN 978-3-86628-343-5
Cardiovascular diseases are the leading cause of
mortality in developed countries. Their pathogenesis and development are
complex and multifactorial, depending on a variety of biochemical and
biomechanical factors and are still not completely understood. Local haemodynamics are increasingly recognised as a key component
to the disease initiation process and yet there is a lack of efficient tools
for imaging such processes in-vivo, leading to a gap in diagnostic capabilities
and limited research possibilities. The objective of this thesis is to
investigate the enhancement of medical images with high-quality blood flow
information and to propose a novel, clinically applicable approach. In an
initial step, several methodological improvements to the current computational
blood flow simulation pipeline are presented focusing principally on surface
mesh generation, computational flow simulation using FEM and FVM and
fluid-structure interaction. Research is further concentrated on creating an
original flow measurement enhancement method, using a database of precomputed
simulations and principal component analysis to interpolate a patient-specific
flow field based on data acquired using medical imaging. The experiments show this
new approach to be highly promising and demonstrate it to be a fast,
clinically-feasible alternative to fully-blown flow simulation.
Author:
Robert McGregor obtained his M.Sc. (Dipl.-Ing.)
degree in Mechanical Engineering from the ETH Zurich in 2004. He performed his
master thesis in collaboration with Zimmer Orthopedics in the field of
experimental orthopedic imaging and then continued working for them in the same
field. From 2006 until 2010 he worked as a research assistant and PhD student
in the field of medical imaging at the Computer Vision Laboratory. In 2010 he
was awarded a PhD degree (Dr. Sc. ETH) from the ETH Zurich for his doctoral
thesis “Enhancing Medical Images with High Quality Blood Flow Information”.
Keywords: Computational Fluid Dynamics, Magnetic Resonance
Imaging, Blood Flow Measurement, Blood Flow Simulation, Mesh Generation, Flow
Measurement Enhancement, Biomedical Flow Imaging
Reihe " Selected Readings in Vision and Graphics
" im Hartung-Gorre Verlag
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